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目的 评价无创正压通气 (NIPPV)对慢性阻塞性肺病 (COPD)急性加重期的治疗价值 ;分析影响疗效的因素。方法 选择符合插管指征COPD患者 ,予NIPPV ,分析其最终预后及与入院时测定指标的相关性。结果 (1)NIPPV治疗成功率 70 8% ;(2 )NIPPV成功组患者与失败组比较 ,COPD病程、体重指数、家庭吸氧率、呼吸频率、血清白蛋白、尿素氮、APACHEⅡ评分均有显著差异 ,而年龄、性别、血气指标、血象、血色素、血肌酐等无相关性 ;(3)NIPPV未出现影响预后的严重并发症。结论 NIPPV治疗COPD急性加重期疗效确切、安全 ;病史资料、病理生理指标对预测治疗效果有一定的意义
Objective To evaluate the value of noninvasive positive pressure ventilation (NIPPV) in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD) and analyze the factors influencing the curative effect. Methods Patients with COPD indications for intubation were enrolled and treated with NIPPV. The final prognosis was analyzed and the correlation with the indexes measured at admission was analyzed. Results (1) The success rate of NIPPV treatment was 70.8%. (2) Compared with the failure group, the duration of COPD, body mass index, family oxygen uptake rate, respiratory rate, serum albumin, urea nitrogen and APACHEⅡwere all significantly higher There were no significant differences in age, gender, blood gas index, hemogram, hemoglobin and serum creatinine. (3) No serious complications were found in NIPPV. Conclusion NIPPV treatment of acute exacerbation of COPD exact and safe; history data, pathophysiological indicators of the prognosis of treatment has some significance