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为确定肾上腺皮质激素是否与消化性溃疡的发生率、复发率及合并症发生率的增加有关,作者对1950~1975年《医学季度累积索引》中所收录的有关皮质激素或促肾上腺皮质激素治疗各种疾患的资料进行后向性分析。结果如下: 整个研究分为二组:第一组为26项前向性、双盲法对照研究,计3,558例;第二组为16项前向性、非双盲法对照研究,计1,773例。已确诊的消化性溃疡发生率:在双盲法研究中,对照组1,491例消化性溃疡发生率为1.0%,而皮质激素治疗组2,067例中为1.4%。两组统计学差异不显著。治疗组溃疡出血率(0.3%)和穿孔率(0.0%)与对
To determine whether adrenocorticotropic hormone and peptic ulcer incidence, recurrence rate and the incidence of complications related to the author of the 1950-1975 “Medical Quarterly Cumulative Index” contained in the corticosteroid or adrenocorticotropic hormone therapy The data of various diseases are analyzed retrospectively. The results were as follows: The whole study was divided into two groups: the first group consisted of 26 prospective, double-blind controlled studies, accounting for 3,558 cases; the second group consisted of 16 prospective, non-double-blind controlled studies . Has confirmed the incidence of peptic ulcer: double-blind study in the control group 1,491 cases of peptic ulcer incidence was 1.0%, while 2,067 cases of corticosteroid group was 1.4%. There was no significant difference between the two groups. Treatment group ulcer bleeding rate (0.3%) and perforation rate (0.0%) with the right