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目的 :探讨感染与冠心病 (CHD)的关系。方法 :选择了 118例冠状动脉造影的患者 ,其中 6 3例冠状动脉造影阳性患者为CHD组 ,5 5例冠状动脉造影阴性者为非CHD组。检测了患者血清幽门螺杆菌抗体 (HpIgG)、肺炎衣原体抗体 (CpnIgG)、巨细胞病毒抗体 (CMVIgG)、单纯疱疹病毒 1抗体 (HSV 1IgG)、单纯疱疹病毒 2抗体 (HSV 2IgG)、腺病毒抗体 (AdenovirusIgG)、同型半胱氨酸 (Hcy)、总胆固醇 (TC)和甘油三酯 (TG)。 结果 :HpIgG、CpnIgG、CMVIgG、HSV 1IgG、HSV 2IgG和adenovirusIgG在两组间差异均无显著性意义 (均 P 0 .0 5 ) ,Hcy、TC和TG在病毒感染阳性与阴性间差异亦无显著性意义 (均P 0 .0 5 )。结论 :Hp、肺炎衣原体、巨细胞病毒、单纯疱疹 1、单纯疱疹 2、腺病毒感染可能与CHD的发病无明显相关
Objective: To investigate the relationship between infection and coronary heart disease (CHD). Methods: A total of 118 patients undergoing coronary angiography were enrolled. Sixty-three patients with CHD were enrolled in the CHD group and 55 were non-CHD patients with negative coronary angiography. Serum H. pylori antibodies (HpIgG), CpnIgG, CMVIgG, HSV 1 IgG, HSV 2 IgG, adenoviral antibody (Adenovirus IgG), homocysteine (Hcy), total cholesterol (TC) and triglyceride (TG). Results: HpIgG, CpnIgG, CMVIgG, HSV 1IgG, HSV 2IgG and adenovirusIgG had no significant difference between the two groups (all P 0 .0 5). There was no significant difference between Hcy, TC and TG in the positive and negative viral infections Sexual significance (all P 0 .0 5). Conclusion: Hp, Chlamydia pneumoniae, cytomegalovirus, herpes simplex 1, herpes simplex 2, adenovirus infection may not be associated with the incidence of CHD