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对荧光涂料激发能源~(147)Pm的生殖毒性进行了研究,观察到胎盘对~(147)Pm进入子体有明显的屏障作用。~(147)Pm在睾丸内的滞留半减期达105d,可见其在睾丸中呈持续性蓄积,很难排除。~(147)Pm可诱发精子畸形,主要呈现无钩精子。而其诱发精原细胞染色体畸变,则以染色单体型畸变为主,对初级精母细胞可产生染色体断片和易位,出现多价体。~(147)Pm可引起活胎率下降,胚胎吸收数增加,而显性骨骼畸形的发生率则与睾丸中~(147)Pm累积吸收剂量间呈正相关。
The reproductive toxicity of 147Pm stimulated by fluorescent coating was studied and it was observed that the placenta had a significant barrier to the entry of 147Pm into the progeny. ~ (147) Pm in the testes retention half-dead up to 105d, showing its continued accumulation in the testis, it is difficult to rule out. ~ (147) Pm can induce sperm deformity, the main non-hook sperm. Chromosome aberration induced by spermatogonia, then the main type of chromosomal aberrations, primary spermatocytes can produce chromosomal fragments and translocations, appear multivalent. ~ (147) Pm caused a decrease in live birth rate and increased embryo absorption, while the incidence of dominant skeletal deformity was positively correlated with cumulative absorbed dose of ~ (147) Pm in testis.