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目的:了解沈阳市出生缺陷变化趋势及其相关因素,并提出有效的干预措施,为各级部门制定政策提供科学依据。方法:对1996～2006年沈阳市出生缺陷资料进行回顾性分析。结果:沈阳市出生缺陷发生率为83.35/万;总唇裂占出生缺陷的首位;出生缺陷的诊断方法以临床诊断为主,其次为超声诊断。结论:加强一级预防是避免出生缺陷发生的关键;加强孕期筛查及产前筛查质量可以降低出生缺陷率。
OBJECTIVE: To understand the changing trend of birth defects in Shenyang and its related factors, and to put forward effective intervention measures to provide scientific basis for the formulation of policies at all levels. Methods: The data of birth defects in Shenyang from 1996 to 2006 were retrospectively analyzed. Results: The incidence of birth defects in Shenyang was 83.35 / million; the total cleft lip accounted for the first place of birth defects; the diagnosis of birth defects was clinically diagnosed, followed by ultrasonography. Conclusion: To strengthen primary prevention is the key to avoid birth defects; to strengthen screening during pregnancy and quality of prenatal screening can reduce the birth defect rate.