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目的:探讨围生期妇女骨量和骨代谢及其影响因素。方法:选取2008～2009年100例孕产妇为研究对象,将其设为观察组,选取同期的100例未孕妇女为对照组,将观察组孕早期、孕中期及孕后期和对照组的血清磷、钙、骨碱性磷酸酶、骨钙素、尿钙/肌酐及抗酒石酸酸性磷酸酶、雌二醇等进行检测及比较。结果:经研究比较发现,随着孕周的增加,观察组孕后期血清磷、钙、骨钙素降低,而则尿钙/肌酐、骨碱性磷酸酶、抗酒石酸酸性磷酸酶、雌二醇升高,孕后期与孕中期、孕前期及对照组比较,P<0.05或P<0.01,有统计学差异。结论:对于围生期妇女进行监测骨量和骨代谢较为重要,以便及时采取补钙措施。
Objective: To investigate the bone mass and bone metabolism in perinatal women and its influencing factors. Methods: 100 maternal women from 2008 to 2009 were selected as the study group. The observation group was selected as the observation group. One hundred non-pregnant women of the same period were selected as the control group. The serum levels of the pregnant women in the early pregnancy, the second trimester, the second trimester and the control group Phosphorus, calcium, bone alkaline phosphatase, osteocalcin, urinary calcium / creatinine and tartrate-resistant acid phosphatase, estradiol were detected and compared. Results: The study found that, with the increase of gestational age, serum phosphorus, calcium and osteocalcin in the observation group decreased during pregnancy, but the urinary calcium / creatinine, bone alkaline phosphatase, tartrate-resistant acid phosphatase, estradiol P <0.05 or P <0.01, there was a significant difference between the first trimester and the third trimester, pre-pregnancy and control group. Conclusion: It is important to monitor bone mass and bone metabolism in perinatal women in order to take timely calcium supplementation.