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目的:检测卵泡期的宫颈黏液(cervical mucus,CM),探讨供精人工授精(Artificial Insemination with donorsperm,AID)的妊娠率与CM分值的关系。方法:参照WHO CM评分标准,评估卵泡期AID手术日的CM,实验室检测CM细胞数、成丝性、羊齿化,目测黏稠度、CM量,CM评分≥10分者选择宫颈内人工授精(cervical insemination,ICI),CM评分<10分者选择宫腔内人工授精(Intrauterine insemination,IUI)。结果:AID1 478周期271周期妊娠,按CM黏稠度、成丝性、羊齿化结晶进行分组,妊娠率差异无统计学意义(P>0.05);按手术日CM细胞数进行分组,妊娠率差异有统计学意义(P<0.05);ICI组妊娠率18.9%、IUI组妊娠率16.6%(P>0.05)。结论:排卵期CM中细胞数量增多是影响AID手术妊娠率的重要因素,CM黏稠度、成丝性、羊齿化均不是影响AID妊娠率的主要因素,CM<10分者选择IUI手术方式可以获得较好的妊娠率。
Objective: To detect the cervical mucus (CM) in follicular phase and investigate the relationship between pregnancy rate and CM score of artificial insemination with donorsperm (AID). Methods: According to the WHO CM scale, CM in follicular phase of AID surgery was evaluated. The number of CM cells in laboratory, silkiness, fern, visual acuity, CM, CM score ≥ 10 were evaluated by intrauterine insemination (ICI), intrauterine insemination (IUI) with CM score <10 points. Results: There was no significant difference in pregnancy rate between 271 cycles of AID1 478 cycle pregnancy and CM consistency, fusiformity and fern crystallization (P> 0.05). According to the number of CM cells on operation day, the difference of pregnancy rate (P <0.05). The pregnancy rate was 18.9% in ICI group and 16.6% in IUI group (P> 0.05). Conclusions: The increase of cell number in CM during ovulation is an important factor affecting the pregnancy rate of AID surgery. CM viscosity, silkiness and sheep tooth are not the main factors affecting the pregnancy rate of AID. Get a better pregnancy rate.