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对20例伴有血氧不足呼吸衰竭及氧合指数大于20的足月/接近足月的新生儿进行Ⅰ或Ⅱ期的PGE1(IPGE1)吸入的可行性、安全性及剂量增加研究。对13例新生儿使用喷雾器持续2h增加剂量吸入IPGE1,间隔1h吸入一氧化氮(第1组),对7例不能吸入一氧化
To investigate the feasibility, safety and dose increase of 20 patients with stage I or II PGE1 (IPGE1) inhalation in 20 neonates with hypoxemic respiratory failure and full-term / near-term oxygenation index> 20. Thirteen newborn infants were challenged with inhaled nitric oxide (group 1) at 2 h intervals using a nebulizer for 2 h at a dose of inhaled IPGE1. Seven patients were unable to inhale nitric oxide