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微量元素在心血管疾病的病因学及发病过程中日益受到重视。与冠心病有关的微量元素的研究目前国内外报告以锌、铜、镁等为多。对冠心病患者血浆镍离子(Ni~(++))变化近年来国内外也报告较多,但国内尚未见文献报告。本文作一简要综述。一、镍的代谢及生理作用镍最初在60年代曾被认为是人体内的一种“异常”微量元素,到70年代始认为可能是人的必需微量元素,后经一系列的研究逐渐明确镍是人体所必需的超微量元素之一,存在于人体各组织中。现有的研究结果提示人每日从食物中摄取镍为170~700微克,每日镍需要量为50微克/公斤。动物性食物及高脂饮食的镍含量低。含
Trace elements in the etiology and pathogenesis of cardiovascular disease is increasingly valued. The study of trace elements related to coronary heart disease at home and abroad at present report to zinc, copper, magnesium and more. Plasma nickel ion (Ni ~ (++)) changes in patients with coronary heart disease also reported more at home and abroad in recent years, but no literature has been reported in China. This article gives a brief overview. First, the metabolic and physiological role of nickel Nickel was originally considered in the 60s as an “abnormal” trace elements in the human body, to the beginning of the 1970s may be considered as essential trace elements, after a series of studies gradually clear nickel It is one of the trace elements essential for the human body and exists in various tissues of the human body. Existing research suggests that people daily intake of 170 to 700 micrograms of nickel from food, daily nickel requirement of 50 micrograms / kg. Low levels of nickel in animal foods and high-fat diets. Contains