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目的探讨米索前列醇在人工流产术前用于软化宫颈的临床效果及安全性。方法将50例妊娠70～84d,要求行人工流产术的妇女随机分成两组,试验组25例用米索前列醇0.2mg于人工流产术前4～6h置于阴道后穹隆;对照组25例于手术前10～12h将16～18号橡皮导尿管置于宫腔。观察两组病例手术时宫颈软化程度、宫口大小、出血量、子宫收缩情况、人工流产综合征的发生率。结果两组妇女宫颈软化程度、子宫收缩情况、出血量、人工流产综合征的差异有统计学意义(P<0.01)。结论人工流产术前阴道后穹隆放置米索前列醇,软化宫颈、扩张宫颈简便、安全、有效,能有效减轻人工流产时的痛苦,预防人工流产并发症的发生。
Objective To investigate the clinical effect and safety of misoprostol in softening cervix before artificial abortion. Methods A total of 50 women with gestational age from 70 to 84 days who underwent induced abortion were randomly divided into two groups. In the test group, 25 patients were treated with misoprostol 0.2 mg in the vaginal posterior fornix 4 to 6 hours before induced abortion. In the control group, 25 patients 10 ~ 12h before surgery will be 16 to 18 rubber catheter placed in the uterine cavity. The incidence of cervical softening, cervix size, bleeding volume, uterine contractions and abortion syndrome were observed during operation in two groups. Results There were significant differences in the degree of cervical softening, uterine contractions, bleeding and abortion syndrome between the two groups (P <0.01). CONCLUSION: Misoprostol is placed in the vaginal posterior fornix before artificial abortion. It softens the cervix and expands the cervix. It is simple, safe and effective. It can effectively reduce the pain in induced abortion and prevent the occurrence of complications of induced abortion.