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目的观察血必净治疗脓毒症疗效。方法使用随机平行对照方法 ,将62例住院患者按随机数字表法分为两组。治疗前及治疗后24h、72h采血检查血浆胱抑素。对照组31例予经验型抗感染治疗,头孢他啶,2 g/次,2次/d。治疗组31例100 ml血必净+150 ml生理盐水,1次/d,静脉滴注。连续治疗7 d为1疗程。观测临床症状、胱抑素C、不良反应。连续治疗2疗程,判定疗效。结果治疗组痊愈12例,显效8例,有效5例,无效6例,总有效率80.65%。对照组痊愈8例,显效3例,有效6例,无效14例,总有效率54.85%。治疗组疗效优于对照组(P<0.05)。胱抑素C两组有改善(P<0.05,P>0.05),治疗组改善优于对照组(P<0.01)。结论血必净治疗脓毒症效果显著,值得推广。
Objective To observe the effect of Xuebijing in the treatment of sepsis. Methods Using randomized parallel method, 62 inpatients were divided into two groups according to random number table. Before treatment and 24h, 72h after treatment, blood samples were collected for detection of cystatin. The control group, 31 cases of empirical anti-infective treatment, ceftazidime, 2 g / times, 2 times / d. The treatment group, 31 cases of 100 ml Xuebijing +150 ml saline, 1 / d, intravenous drip. Continuous treatment of 7 d for a course of treatment. Observed clinical symptoms, cystatin C, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. Results The treatment group cured 12 cases, markedly effective in 8 cases, effective in 5 cases, ineffective in 6 cases, the total effective rate was 80.65%. The control group recovered in 8 cases, 3 cases markedly effective in 6 cases, 14 cases ineffective, the total effective rate was 54.85%. The treatment group was better than the control group (P <0.05). Cystatin C improved in both groups (P <0.05, P> 0.05), the treatment group improved better than the control group (P <0.01). Conclusion Xuebijing treatment of sepsis significant effect, it is worth promoting.