论文部分内容阅读
鲍曼不动杆菌是临床常见感染菌,耐药性日益增强。其多重耐药性与可长期存活性将导致菌膜的形成,而这种可以抵抗抗菌素治疗的菌膜有着复杂的机构,在复杂结构中起到形成菌膜、维持菌膜稳定性的两个重要组成部分为胞外多糖(EPS)和菌膜相关性蛋白(the biofilm-associated protein,Bap),促使鲍曼不动杆菌躲避宿主免疫系统的攻击,因此针对鲍曼不动杆菌的治疗也愈发困难。
Acinetobacter baumannii is a common clinical infection bacteria, drug resistance is increasing. Its multi-drug resistance and long-term viability will lead to the formation of the bacterial membrane, which can resist the antibiotic treatment of the membrane has a complex mechanism in the complex structure of the formation of bacteria, to maintain the stability of the membrane two Important components of the extracellular polysaccharide (EPS) and the membrane associated protein (the biofilm-associated protein, Bap), prompting Acinetobacter baumannii to evade host immune system attack, so Acinetobacter baumannii treatment more Difficult to send.