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临床短期研究显示,非类固醇抗炎药物(NSAID)可能对降压治疗的效果产生影响,但这些研究既未包括足够数量的老年,也未对长期应用NSAID和血压的关系作出评价,为此本文进行了研究。方法对某一地区年龄≥65岁的老年人作调查,记录调查前两周所用各种药物的名称与剂量。两周内处方用过NSAID或一周内非处方用过NSAID者定为本文研究对象。其中男性70例,年龄73.8±6岁;女性165例,年龄74.8±6.8岁;男性中有42例,女性中有91例同时应用降压药物。所确定的未应用过NSAID的对照组亦为男性70例,女性165例。应用和未用NSAID组不仅在例数、性别和同时
Short-term clinical trials have shown that non-steroidal anti-inflammatory drugs (NSAIDs) may have an impact on the efficacy of antihypertensive therapy, but neither of these studies include a sufficient number of elderly nor do they evaluate the long-term use of NSAIDs and blood pressure Were studied. Methods Aged 65 years or older in a certain area of the elderly for investigation, record the names and doses of various drugs used two weeks before the survey. Prescriptions used within two weeks of NSAID or non-a week within the NSAID were used as the object of this study. There were 70 males, aged 73.8 ± 6 years; 165 females, aged 74.8 ± 6.8 years; 42 males and 91 females with antihypertensive drugs. The control group that had not been used for NSAID was also found in 70 males and 165 females. The applied and unused NSAID groups are not only in the number of cases, the gender and the mean time