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目的建立我国病原微生物材料安全数据单的编写要求,促进实验室生物安全管理的规范统一。方法通过查阅文献,参考材料安全数据单的一般编写规则,结合病原微生物生物安全管理的需求,研究其编写内容。结果病原微生物材料安全数据单具有五个信息域,通过逐级分析获得13个一级编写项目和45个二级编写项目,然后应用风险评估方法确定数据单中二级编写项目的具体内容。结论本研究提出了病原微生物材料安全数据单编写规范,有效地提高了病原微生物安全相关信息的整合度,为实验室风险管理、人员培训和事故调查等活动提供至关重要的分析依据。
Objective To establish the compilation requirements of safety data sheets of pathogenic microorganisms in our country and to promote the standardization and unification of laboratory biosafety management. Methods According to the general rules of compilation of literature and reference material safety data sheets and the requirements of biosecurity management of pathogenic microorganisms, the contents of the compilation were studied. Results There were five information fields in the material safety data sheet of pathogenic microorganisms. Thirteen primary-level and 45 secondary-level written projects were obtained by level-by-level analysis, and then the risk assessment method was used to determine the specific content of the secondary level written project in the data sheet. Conclusion This study proposed the compilation of safety data sheet of pathogenic microorganism material, which effectively improved the integration degree of pathogenic microorganism safety-related information and provided crucial analysis basis for laboratory risk management, personnel training and accident investigation.