论文部分内容阅读
合成了以4,4’-二环己基甲烷二异氰酸酯(HMDI)和乙二胺(EDA)为硬段、聚碳酸六亚甲基酯二醇(PHC)为软段的聚酯型聚氨酯脲(PUU),并用聚氧乙烯和肝素(heparin)对其进行了表面改性。通过红外光谱、X射线光电子能谱、接触角等研究了PUU材料的表面结构和性能。实验结果表明,利用室温等离子体方法,成功在PUU表面引入了活性点,引发丙烯酸的表面接枝聚合,经与过量的双端基PEO反应,成功地在PUU表面引入PEO链,并进一步成功地在PUU表面固定了肝素。研究发现,通过PEO和肝素的表面改性,PUU材料的接触角由68°减小到45°(PUU-PEO)和40°(PUU-PEO-heparin),有效提高了PUU表面的亲水性。在相同条件下,分子量较小PEO有较好的接枝效率和较好的肝素固定能力。
A series of polyurethane polyurethanes were synthesized using 4,4’-dicyclohexylmethane diisocyanate (HMDI) and ethylenediamine (EDA) as hard segments and polyhexamethylene carbonate diol (PHC) as soft segments PUU) and surface modified with polyoxyethylene and heparin. The surface structure and properties of PUU were studied by infrared spectroscopy, X-ray photoelectron spectroscopy and contact angle. The experimental results show that the active site is successfully introduced into the surface of the PUU by the room temperature plasma method to initiate the surface graft polymerization of acrylic acid, and the PEO chain is successfully introduced into the surface of the PUU through the reaction with the excess double-ended PEO. Heparin is immobilized on the PUU surface. It was found that the contact angle of PUU decreased from 68 ° to 45 ° (PUU-PEO) and 40 ° (PUU-PEO-heparin) by the surface modification of PEO and heparin, which effectively improved the hydrophilicity of PUU surface . Under the same conditions, the smaller molecular weight PEO has better grafting efficiency and better heparin fixation ability.