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应用放射免疫分析法测定了安静状态下43例充血性心力衰竭病人(NYHA心功能Ⅱ~Ⅳ级)血浆神经肽Y(NPY)的含量,并与20例正常人对照。结果表明,心衰病人组血浆NPY含量明显高于正常对照组(P<0.001)。并探讨了NPY在心力衰竭中的临床意义。
Radioimmunoassay was used to determine plasma neuropeptide Y (NPY) levels in 43 patients with congestive heart failure (NYHA functional class Ⅱ ~ Ⅳ) at rest and compared with 20 healthy controls. The results showed that plasma NPY levels in patients with heart failure were significantly higher than those in the normal control group (P <0.001). And explored the clinical significance of NPY in heart failure.