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高强度的声音可引发暂时性或永久性的听觉阈移,阈移除可能为声音作用于听神经及听觉中枢的结果外,尚可能由螺旋器细胞内代谢失调及耳蜗结构和超微结构的损伤所引起。据调查得知,至今尚无有关噪声损伤后细胞内离子变化的超微组织化学研究的报道。该文旨在进一步揭示爆震性噪声损伤后螺旋器的超微结构改变及探索此类噪声损伤细胞内钙离子分布的超微组织化学实验方法。选用健康、耳廓反射正常、无中耳疾患史,体重250~300g的豚鼠4只,置于隔音仓,暴露于6次间隔为10秒
High-intensity sounds can lead to temporary or permanent auditory threshold shift, threshold removal may be the role of sound in the auditory nerve and auditory center results, but also by the spiral cell metabolism disorders and cochlear structure and ultrastructure damage Caused. According to the survey, there have been no reports on the ultrastructural chemistry of intracellular ion changes after noise injury. The purpose of this paper is to further reveal ultrastructural changes in the spirocharger after detonation noise damage and to explore the ultrastructural chemistry experimental method of intracellular calcium distribution in such noise-damaged cells. Selection of healthy, normal auricle reflex, no history of middle ear disease, weight 250 ~ 300g of guinea pigs 4, placed in a soundproof warehouse, exposure to six intervals of 10 seconds