心得安减少食管曲张静脉出血的早期复发

• 机 构: 瑞典Basle市Basle大学胃肠病学科,瑞典Basle市Basle大学重点医护科,瑞典Basle市Basle大学重点内科
• 出 处: 临床荟萃
• 发表日期: 1989年06期
• 关键词: 早期复发 曲张静脉 心得安 生长激素抑制素 硬化疗法 气囊填塞 β-阻滞剂 再出血率 食管 阻滞剂

迄今治疗努力主要集中于用气囊填塞、加压素或其衍生物、生长激素抑制素或硬化疗法来即刻控制急性食管曲张静脉出血。在长期预防再出血方面,试用过硬化疗法和β-阻滞剂。鉴于许多出血复发系发生于开始出血后初2周,对如何防止其发生又所知甚少,故控制出血的早期复发具有重要意义,特别是因为减少早期再出血率常被认为可增加长期存活。

Treatment efforts to date have focused primarily on the immediate control of acute variceal bleeding with balloon occlusion, vasopressin or its derivatives, somatostatin or sclerotherapy. In the long-term prevention of rebleeding, the trial of sclerotherapy and β-blockers. Given that many hemorrhage recurrences occur at the first 2 weeks after the onset of bleeding and little is known about how to prevent it, controlling early recurrence of bleeding is important, especially since reducing early rebleeding rates is often thought to increase long-term survival .