阵发性房颤患者血浆D-Dimer、Fg和FDP水平测定及其意义

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目的 观察阵发性房颤患者血浆中D-二聚体纤维蛋白原及纤维蛋白降解产物水平变化,并探讨其临床意义。方法 阵发性房颤组患者22例,对照组14例,均抽取肘静脉血检测血浆D二聚体、纤维蛋白原、纤维蛋白降解产物的水平。结果 阵发性房颤组患者血浆D二聚体水平(251.4±62.3)ng/ml明显高于对照组(205.1±49.2)ng/ml(t=2.349,P<0.05);而纤维蛋白原、纤维蛋白降解产物水平(268.1±50.2)mg/dl、(3.01±1.12)mg/L与对照组(242.7±42.8)mg/L、(2.55±1.24)mg/L相比无明显变化(t=1.813、1.153,P>0.05)。结论 提示阵发性房颤患者可能存在血栓前状态,必要时应给予抗凝治疗。
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