论文部分内容阅读
目的 :探讨儿童肾病合并水痘病毒感染的治疗。 方法 :通过 10例肾病患儿合并水痘病毒感染 ,其中微小病变型 3例 ,系膜增殖性肾小球肾炎 6例 ,系膜增殖性伴新月体形成 1例 ,有中、轻度水痘病毒感染 9例 ,重度感染1例 ;用干扰素、阿昔洛韦、丙种球蛋白或血浆、鲜血、血小板悬液治疗 7例。 结果 :9例治愈 ,死亡 1例。 10例患儿实验室检查 lg G、C3、C4均低下。 结论 :肾病患儿免疫功能低下 ,糖皮质激素等免疫抑制剂和细胞毒类药物应用 ,极易感染水痘病毒或使体内静止的水痘病毒重新激活、增殖和扩散 ,从而加重肾的病变 ,严重者可引起死亡 ,故必须采取综合性治疗和预防 ,方能避免肾病患儿感染水痘病毒
Objective: To investigate the treatment of childhood nephropathy with varicella virus infection. Methods: 10 cases of children with nephropathy were infected with varicella virus. Among them, 3 cases were minimal lesion, 6 cases were mesangial proliferative glomerulonephritis, 1 case was mesangial proliferative crescent. There were moderate and mild varicella virus 9 cases were infected and 1 case was severe infection. Seven cases were treated with interferon, acyclovir, gamma globulin or plasma, blood and platelet suspension. Results: 9 cases were cured and 1 died. 10 cases of children with laboratory tests lg G, C3, C4 are low. CONCLUSIONS: Children with nephrotic syndrome have immunocompromised immune suppressive agents such as glucocorticoids and cytotoxic drugs, which are highly susceptible to or infected with the varicella virus. This results in the reactivation, proliferation and spread of the varicella virus in the body, thereby aggravating renal pathology. In severe cases, Can cause death, it is necessary to take comprehensive treatment and prevention, in order to avoid children with renal disease varicella virus