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目的探讨早中期孕妇贫血发生情况与铁储存情况的关系,为临床提供妊娠贫血的实验室资料。方法测定孕早期和孕中期432名孕妇的贫血相关指标RBC、Hb、HCT、MCV、MCH、MCHC,同时检测血清铁蛋白(SF),血清可溶性转铁蛋白受体(STfR)。结果 163名早期孕妇患者贫血患病率为19.52%,269名中期孕妇贫血患病率为38.31%。孕早期组和孕中期组铁减少患病率分别为14.02%和32.18%。孕中期与孕早期组相比SF显著降低,STfR显著增高。结论孕中期妊娠贫血发生率及铁减少患病率显著高于孕早期组,差异均有统计学意义(P<0.05);与孕早期组相比,孕中期Hb、SF显著降低,STfR显著增高(P<0.05)。
Objective To investigate the relationship between the incidence of anemia in early and mid-term pregnant women and the status of iron storage and to provide laboratory data on anemia of pregnancy. Methods The anemia related indicators RBC, Hb, HCT, MCV, MCH and MCHC of 432 pregnant women in the first trimester and the second trimester were determined. Serum ferritin (SF) and serum soluble transferrin receptor (STfR) were detected simultaneously. Results The prevalence of anemia in 163 early pregnant women was 19.52%. The prevalence of anemia in 269 middle-term pregnant women was 38.31%. Premature pregnancy group and the second trimester group decreased iron prevalence rates were 14.02% and 32.18%. Compared with the first trimester of pregnancy, SF decreased significantly and STfR increased significantly. Conclusions The prevalence of pregnancy-induced anemia and iron reduction in the second trimester of pregnancy are significantly higher than those in the first trimester of pregnancy (P <0.05). Compared with the first trimester of pregnancy, the levels of Hb and SF are significantly decreased and the STfR are significantly increased (P <0.05).