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对7例患者肾移植术后并发重症病毒性肝炎的病回进行了分析。发现所有患者均为HBSAg阳性的HBV感染者，2例重叠HCV感染，HAV和HDV重叠感染各1例。表明HBV感染及在此基础上其它肝炎病毒合并感染是发生重症肝炎的主要原因；治疗过程中环孢素A的应用和它所引起的肝肾毒性是移植后重症肝炎发生和影响患者预后的一个重要因素。提出应慎重考虑HBV感染者的肾移植适应症，有HCV、HDV重叠感染者不宜施行肾移植术。对HBsAg阳性肾移植患者应加强术后肝功能的监测，及早应用保肝药物。
Seven patients with renal failure after severe viral hepatitis were analyzed. All patients were found to have HBSAg-positive HBV infection, two overlapping HCV infections, and one HAV and HDV overlap infection. It is indicated that HBV infection and other hepatitis viruses co-infection are the main causes of severe hepatitis. The application of cyclosporine A and the hepatotoxicity caused by it during the course of treatment are important for the occurrence of severe hepatitis after transplantation and the prognosis of patients factor. It is proposed that patients with HBV infection should be carefully considered indications of renal transplantation, HCV, HDV overlap should not be performed renal transplant recipients. HBsAg-positive renal transplantation patients should strengthen the monitoring of postoperative liver function, early application of hepatoprotective drugs.