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近年来,尽管用于临床的抗生素种类繁多,但肺部感染的病死率仍较高。说明抗生素的选择和伍用在提高临床疗效方面占有重要地位。就此谈谈我们的体会。一、细菌性肺炎由于抗生素的广泛应用,肺部感染的病原已发生很大改变。医院外感染仍以肺炎球菌为多见,但金黄色葡萄球菌及革兰氏阴性杆菌明显增多,后者尤在危重病儿多见。医院内肺部感染的病原中,肺炎、溶血性链球菌及流感杆菌等比例下降,需氧革兰氏阴性杆菌渐见增多(肺炎、绿脓及大肠杆菌等其他肠道杆菌),耐青霉素G的金黄色葡萄球菌(金葡菌)增高。故对肺部感染必需首先获得可靠的病原学诊断,作为选用
In recent years, despite the wide variety of antibiotics used clinically, the mortality rate of lung infections is still high. This shows that the choice of antibiotics and drugs play an important role in improving clinical efficacy. Talk about our experience First, bacterial pneumonia Due to the widespread use of antibiotics, the pathogen of pulmonary infection has undergone great changes. Nosocomial infection is still more common with pneumococcal, but Staphylococcus aureus and Gram-negative bacilli increased significantly, the latter especially in critically ill children more common. The proportion of pneumonia, hemolytic streptococcus and influenza bacilli decreased in the pathogen of pulmonary infection in the hospital, and aerobic Gram-negative bacilli increased gradually (pneumonia, pyorrhea and other intestinal bacilli such as Escherichia coli), penicillin-resistant G Of Staphylococcus aureus (Staphylococcus aureus) increased. Therefore, the first need to obtain a reliable pulmonary etiology of pathogenic diagnosis, as an option