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目的评价米非司酮用于利凡诺中期引产的效果及安全性。 方法 96例中期妊振患者随机分为 3组。组 1:利凡诺引产后每 12h口服米非司酮 5 0mg ,共 3d ;组 2 :每 12h口服米非司酮 5 0mg ,共 2d ,48h后利凡诺引产 ;对照组单行利凡诺引产。观察 3组宫缩发动时间、宫缩至引产结束时间、引产总时间、副反应、阴道流血天数、出血量和月经复潮天数。 结果米非司酮促使宫缩发生、缩短引产时间、不增加阴道出血时间和出血量、不影响月经恢复 ,不需清宫、无特殊副反应。其中组 2的疗效更为明显。 结论利凡诺和米非司酮在中期引产合并使用可显著缩短引产时间 ,无特殊副反应 ,不需清宫。尤以口服米非司酮 2 0 0mg ,48h后利凡诺引产效果最佳
Objective To evaluate the efficacy and safety of mifepristone in the mid-term induction of rivanol. Methods Ninety-six patients with metaphase pregnancy were randomly divided into three groups. Group 1: rivanol after induction of labor every 12h oral mifepristone 50mg, a total of 3d; group 2: every 12h oral mifepristone 50mg, a total of 2d, 48h after rivanol abortion; control group rivanol Induction. The duration of contractions, the total time of induced abortion, the side effects, the days of vaginal bleeding, the amount of bleeding and the days of menstrual cramps were observed. Results Mifepristone to promote uterine contractions, shorten the time of induction of labor, do not increase the vaginal bleeding time and bleeding, does not affect menstruation recovery, without the Qing, no special side effects. The effect of group 2 is more obvious. Conclusions Both rivanol and mifepristone combined with induction of labor during the second trimester could shorten the time of induction of labor, without special side effects and without clearance. Especially oral mifepristone 200mg, 48h after rivanol induction of labor best