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细菌性痢疾(以下简称菌痢)是儿科常见的传染病,我国发病率仍较高,其流行多是福氏志贺菌引起,易产生耐药性,如氨苄西林、复方新诺明等,耐药率已达90％左右,不宜再选用。氨基糖苷类的耳肾毒性,喹喏酮类可能对儿童软骨发育产生潜在的影响,第二、三代头孢菌素的价格昂贵等因素.在不同医院,针对不同耐药情况和临床医师用药的顾忌,其选择的一线药物不尽相同。针对这一现状,现对国内近年抗菌药应用现状做一总结,以供临床参考。1 阿米卡星 常用量每日8～10mg/kg,一次静滴或肌注。也
Bacillary dysentery (hereinafter referred to as bacillary dysentery) is a common pediatric infectious diseases, the incidence is still high in our country, its prevalence is caused by Shigella flexneri easily lead to drug resistance, such as ampicillin, cotrimoxazole, Resistance rate has reached 90%, should not be selected. Aminoglycosides ototoxicity, quinolones may have a potential impact on children’s cartilage development, the second and third generation cephalosporins are expensive and so on. In different hospitals, for different drug resistance and clinicians medication scruples , The choice of first-line drugs vary. In response to this situation, now the status of domestic antibacterial drugs in recent years to make a summary for clinical reference. Amikacin daily dose of 8 ~ 10mg / kg, an intravenous infusion or intramuscular injection. and also