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肥厚型心肌病(HC)的处理有两个不同却又相关的目标:改善症状及识别有心脏猝死危险的病人。药物治疗可以改善大多数患者的症状,而外科手术如间隔肌部分切除术或二尖瓣置换术可用于那些对药物无反应的梗阻性疾病患者。两个手术又是减低静息和激发状态下流出道压力梯度、降低左室舒张末期压、明显改善症状的有效措施。令人遗憾的是上述治疗方法均有不足之处,维拉帕米可促使肺水肿,特别易发生于有显著静息时流出道压力阶差和高左室舒张末期压的患者;β-阻滞剂常引起疲劳,且两药均可导致传导障碍。手术可缓解症状,但也有3-16％
Hypertrophic cardiomyopathy (HC) has two different but related goals: improving symptoms and identifying patients at risk of sudden cardiac death. Medication can improve the symptoms in most patients, and surgical procedures such as partial myomectomy or mitral valve replacement can be used in patients with obstructive disease that do not respond to drugs. Both operations are also effective measures to reduce the pressure gradient of the outflow tract at resting and excited states, reduce left ventricular end-diastolic pressure, and significantly improve symptoms. Regrettably, these treatments have drawbacks. Verapamil causes pulmonary edema, and is particularly prevalent in patients with significant differences in outflow tract pressure gradient and high end-diastolic pressure at rest; Dystabilizers often cause fatigue, and both drugs can lead to conduction disorders. Surgery can relieve symptoms, but there are 3-16%