论文部分内容阅读
为了探讨新生儿脐血β２－ＭＧ与新生儿ＡＢＯ溶血病（称ＡＢＯＨＤＮ）的关系，应用放射免疫法对８０例新生儿脐血β２－ＭＧ进行测定，同时测定脐血胆红素浓度，结果表明，脐血β２－ＭＧ越高，ＡＢＯＨＤＮ发生率越高，脐血β２－ＭＧ含量与ＡＢＯＨＤＮ的发生呈正相关（Ｐ＜０．０５），经统计学分析，以脐血β２－ＭＧ≥２５０μｇ／ｍｌ为指标，敏感性及特异性分别为６９７％、７９４％。以脐血胆红素≥４０μｍｏｌ／Ｌ为指标，敏感性及特异性分别为６０８％、７０６％，前者敏感性及特异性均大于后者。提示测定脐血β２－ＭＧ可以早期预测ＡＢＯＨＤＮ的发生。
To investigate the relationship between neonatal umbilical cord blood β2-MG and neonatal ABO hemolytic disease (called ABOHDN), radioimmunoassay was used to determine cord blood β2-MG in 80 neonates and to determine the concentration of umbilical cord blood bilirubin at the same time , The higher the umbilical blood β2-MG, the higher the incidence of ABOHDN, the cord blood β2-MG content was positively correlated with the occurrence of ABOHDN (P <0.05) .According to statistical analysis, umbilical cord blood β2-MG≥250μg / Ml as an indicator, the sensitivity and specificity were 69 7%, 79 4%. To umbilical cord blood bilirubin ≥ 40μmol / L as an indicator, the sensitivity and specificity were 60 8%, 70 6%, the former sensitivity and specificity are greater than the latter. Prompt determination of cord blood β2-MG can predict ABOHDN early.