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本文报导美国俄亥俄州一所中学里,三名无血缘关系的女教师,曾先后在同一教室执教2～5年,18年以后,相继患了肌萎缩性侧索硬化(ALS),并死于其并发症。作者认为她们患ALS是共同的职业环境所致,从统计学观点分析,这种可能性是极小的。例1,1960～1962年在一普通教室里教学,1978年,她35岁时出现了发音及吞咽困难,右手无力,查体发现右手肌肉萎缩,无力,右侧腱反射亢进,1年后发展为全身肌无力、痉挛,语言及吞咽障碍,1979年肌电图(EMG)检查示上下肢均有失神经电位和束颤,确诊为ALS,1980年死于呼吸衰竭。例2,1962～1966年在例1教过学的同一教
This article reports that in a high school in Ohio, three unrelated female teachers in Ohio have taught in the same classroom for two to five years. After 18 years, they have developed amyotrophic lateral sclerosis (ALS) and died of Its complications. The authors believe that they suffer from ALS is a common occupational environment, from a statistical point of view, this possibility is minimal. Example 1, teaching from 1960 to 1962 in a common classroom. In 1978, she developed dysphagia and dysphagia when she was 35 years old. Her right hand was weak. Physical examination showed right ape muscle atrophy, weakness, and excessive right tendon reflexes. After 1 year, she developed For the whole body muscle weakness, spasms, language and swallowing disorders, electromyography (EMG) examination in 1979 showed that both the lower extremity denervation potential and fibrillation, diagnosed as ALS, died of respiratory failure in 1980. Example 2, the same teaching taught in Example 1 from 1962 to 1966