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目的:了解老年人有关细菌性感染伴发热的病原菌及T淋巴细胞亚群变化。方法:对116 例老年细菌感染伴发热的病原菌进行检测,并采用APAAP法观察其外周血T淋巴细胞亚群变化。结果:老年人细菌感染伴发热的病原菌以表皮葡萄球菌、金黄色葡萄球菌以及大肠埃希氏菌等居多,且其外周血中CD3 细胞,CD4 细胞均明显低于正常人(P< 0.05)。结论:老年人细菌感染伴发热与T淋巴细胞功能改变有关。
OBJECTIVE: To understand the changes of pathogens and T lymphocyte subsets in elderly patients with bacterial infection associated with fever. Methods: One hundred and sixty-six elderly patients with bacterial infection and fever were tested for pathogenic bacteria. The changes of T lymphocyte subsets in peripheral blood were detected by APAAP. Results: Staphylococcus epidermidis, Staphylococcus aureus and Escherichia coli were the most common pathogens in the elderly with bacterial infection. The CD3 and CD4 in peripheral blood were significantly lower than those in normal people (P <0.05) ). Conclusion: Geriatric bacterial infection with fever and T lymphocyte function changes.