氧介导的动脉导管收缩作用机制

来源 :临床儿科杂志 | 被引量 : 0次 | 上传用户:QINSHAOKUN1988
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动脉导管是主动脉和肺动脉之间的管道 ,胎儿期肺动脉血大多经未闭的动脉导管入降主动脉 ,但出生后须及时关闭 ,如关闭延迟或不能关闭即为动脉导管未闭。维持宫内动脉导管开放和出生后动脉导管的关闭受体内许多因素调节 ,动脉导管的紧张性调节依赖氧介导的收缩作用和前列腺素(P Artery duct is the conduit between the aorta and the pulmonary artery. Most of the fetal pulmonary arterial blood enters the aorta through the patent ductus arteriosus, but it must be promptly closed after birth. If the closure is delayed or can not be closed, the patent ductus arteriosus is patent ductus arteriosus. Maintaining the intrauterine artery catheter opening and the closure of the ductus arteriosus after birth is regulated by many factors in the recipient. Tension regulation of the ductus depends on oxygen-mediated contractile activity and prostaglandin (P
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