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肝硬化患者由于外周阻力下降、动脉压降低、静息心输出量增加,常处于高动力循环状态,致心肌收缩、舒张功能受损,在休息时可无心功能不全表现,但在生理、病理、药理、手术等应激情况下,可出现心功能不全甚至心力衰竭,此种现象称为肝硬化心肌病(Cirrhotic cardiomyopathy,CCM),是肝硬化的并发症之一,近年逐渐受到临床的重视。本文对近年来CCM的发病机制、病理、诊断、治疗等方面的研究进展作一综述。
Patients with cirrhosis due to decreased peripheral resistance, decreased arterial pressure, resting cardiac output increased, often in high power cycling, resulting in myocardial contractility, diastolic dysfunction, at rest, no heart failure, but in physiology, pathology, Pharmacology, surgery and other stress conditions, there may be cardiac insufficiency and even heart failure, a phenomenon known as cirrhotic cardiomyopathy (Cirrhotic cardiomyopathy, CCM), is one of the complications of cirrhosis in recent years gradually been clinically valued. This review summarizes the research progress on the pathogenesis, pathology, diagnosis and treatment of CCM in recent years.