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目的研究东菱迪芙联合低分子肝素和阿司匹林对急性脑梗死的治疗效果及凝血指标的影响。方法对120例急性脑梗死患者随机分成治疗组(应用东菱迪芙、低分子肝素和阿司匹林60例)和对照组(不用东菱迪芙、低分子肝素和阿司匹林60例)。2组均于治疗前后进行神经功能缺损评分,进行对比评定临床疗效,凝血指标。结果治疗组总有效率优于对照组(P<0.01),神经功能恢复与对照组比较有显著性(P<0.05),纤维蛋白原明显降低与对照组有显著差异(P<0.05)。结论东菱迪芙联合低分子肝素和阿司匹林治疗急性脑梗死安全有效。
Objective To study the effect of Donglingdufu combined with low molecular weight heparin and aspirin on acute cerebral infarction and the effect of coagulation index. Methods A total of 120 patients with acute cerebral infarction were randomly divided into treatment group (Donglingdefu, low molecular weight heparin and aspirin 60 cases) and control group (without Donglingdufu, low molecular weight heparin and aspirin 60 cases). The neurological deficits were evaluated before and after treatment in both groups, and the clinical curative effect and coagulation index were compared. Results The total effective rate of the treatment group was better than that of the control group (P <0.01). The recovery of neurological function was significant (P <0.05) and fibrinogen was significantly lower than that of the control group (P <0.05). Conclusion Dong Ling Du Fu combined with low molecular weight heparin and aspirin in the treatment of acute cerebral infarction safe and effective.