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皮肤免疫学研究皮肤免疫系统在维持人体健康和在疾病发生中的机理。皮肤不仅具有一般的屏障作用,而且还能合成大量具有不同生物活性的物质,是免疫防御的一条补充防线。 Kondo(1922)最早阐述了表皮内淋巴细胞。Fichtelius等(1970)指出皮肤是第一级淋巴器官,并认为到达皮肤的淋巴细胞大多是不成熟的,但在表皮内或在近表皮的真皮内很快成熟起来。
Skin immunology studies the mechanisms by which the skin’s immune system plays a role in maintaining human health and in the development of the disease. Skin not only has a general barrier function, but also can synthesize a large number of substances with different biological activity, which is a supplementary defense of immune defense. Kondo (1922) first described intraepidermal lymphocytes. Fichtelius et al. (1970) pointed out that the skin is the primary lymphoid organ and that most of the lymphocytes reaching the skin are immature, but rapidly mature in the epidermis or in the near-epidermal dermis.