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目的:系统评价穴位贴敷治疗支气管哮喘(bronchial asthma,BA)的临床疗效及安全性.方法:计算机检索Pubmed、中国生物医学文献数据库(CBM)、中国期刊全文数据库(CNKI)、中文期刊全文数据库(VIP)、万方数字化期刊全文数据库(WANFANG DATA),检索年限至2016年7月,以临床疗效、肺功能、哮喘控制测试(asthma control test,ACT)评分、中医证候积分、不良反应为效应指标,采用RevMan 5.3软件进行数据分析.结果:共纳入14篇研究,1,953例患者,Meta分析结果显示穴位贴敷治疗BA的临床总有效率优于对照组[RR=1.20,95％CI(1.14,1.27)],肺功能改善明显优于对照组,FEV1％变化明显低于对照组[WMD=7.82,95％CI(6.64,8.99)];PEF值变化明显高于对照组[SMD=0.72,95％ CI(0.50,0.94)];FEV1/FVC％变化明显高于对照组[SMD=0.57,95％CI(0.21,0.94)],ACT评分明显高于对照组,差异有统计学意义[WMD=1.31,95％CI(0.82,1.80)],同时穴位贴敷疗法不良反应少.结论:穴位贴敷能有效缓解支气管哮喘患者的临床症状,改善患者的肺功能,提高生活质量.但由于纳入研究质量和数量限制,尚需大样本、多中心、高质量的随机对照试验进行验证.“,”Objective:To systematically evaluate the Clinical effects and safety of acupoint application in the treatment of bronchial asthma.Methods:We explored literature from the Pubmed,CBM,CNKI,VIP,WANFANG DATA from build library time until July 2016,to put the clinical effect,pulmonary function test (PFT),score of asthma control test (ACT),score of TCM symptom and adverse reaction as the effective index.Then,meta-analysis was performed using RevMan 5.3 software.Results:A total of 14 RCTs involving 1,953 participants were included.The results of rcta-analysis showed that the total clinical effective rate in the acupoint application group was higher than that of control group [RR=1.20,95％CI (1.14,1.27).Improvement of PFT was significantly better than that of control group [The change of FEV1％ was significantly lower than those in control group [WMD=7.82,95％ CI (6.64,8.99)].The change of PEF value was significantly higher than that of control group [SMD=0.72,95％CI(0.50,0.94)];The change of FEV1/FVC％ was significantly higher than that of control group [SMD=0.57,95％CI (0.21,0.94)].Scores of ACT were significantly higher than those in control group.There was profoundly significant difference in ACT between two groups [WMD=1.31,95％CI (0.82,1.80)].At the same time,the adverse reaction of the therapy of acupoint application is little.Conclusion:Acupoint application can effectively alleviate the clinical symptoms of bronchial asthma patients,improve the patient's PFT,and increase the quality of life.However,due to the limitation of the quality and quantity of included studies,the above conclusion needs to be further verified by more large samples,multi center and high quality studies.