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作者以谷草转氨酶/谷丙转氨酶(AST/ALT)比值,应用于评价一组新生儿巨细胞病毒包涵体病(CID)预后状况。知肝脏径度受损时细胞浆内的线粒体等仍保持完整。仅胞浆内酶释出,共AST/ALT比为0.6,故血清内该比值亦较低;当肝脏严重受损时,细胞浆及线粒体同时受累,两者总AST/ALT比为3.0,比值明显增高。动态监测此值,是评价CID预后的早期可靠指标。
The authors used aspartate aminotransferase / alanine aminotransferase (AST / ALT) ratio, used to evaluate a group of neonatal cytomegalovirus inclusion body disease (CID) prognosis. Mitochondria within the cytoplasm remain intact when the diameter of the liver is compromised. Only the intracellular enzyme release, a total AST / ALT ratio of 0.6, so the serum ratio is lower; when the liver is severely damaged, the cytoplasm and mitochondria simultaneously affected both total AST / ALT ratio of 3.0, the ratio Significantly higher. Dynamic monitoring of this value is an early reliable indicator of CID prognosis.