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目的:探讨黄体酮联合坦索罗辛对输尿管下段结石的疗效。方法:将输尿管结石患者100例,随机分为对照组和治疗组,每组50例,治疗组给予坦索罗辛及黄体酮,对照组给予坦索罗辛。结果:治疗组的结石排出率为80%(40/50),高于对照组的52%(26/50),治疗组的排石时间、肾绞痛发生率、镇痛剂使用率均低于对照组。两组在治疗期间均未发现明显的不良反应,无因不能耐受而退出者。结论:黄体酮联合盐酸坦索罗辛胶囊治疗输尿管下段结石,可以减少结石排出时间,增加结石的排出率,减少治疗期间肾绞痛的再发作次数,疗效显著。
Objective: To investigate the effect of progesterone combined with tamsulosin on the lower ureteral calculi. Methods: One hundred patients with ureteral calculi were randomly divided into control group and treatment group, with 50 patients in each group. Tamsomosin and progesterone were given to the treatment group and tamsulosin was given to the control group. Results: The rate of stone excretion was 80% (40/50) in the treatment group, which was higher than that in the control group (52/50). The time to stone discharging, the incidence of renal colic and the usage of analgesic in the treatment group were all lower In the control group. No significant adverse reactions were found in the two groups during treatment, no withdrawal due to intolerance. Conclusion: Progesterone combined with tamsulosin hydrochloride capsule in the treatment of lower ureteral calculi can reduce the time of stone discharge, increase the rate of stone excretion and reduce the number of reoccurrence of renal colic during treatment. The curative effect is remarkable.