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免眼巩膜表面进行了电凝实验,测定了房水中蛋白(PRO)、前列腺素E_2(PGE_2)、前列环素(PGI_2)和血栓素(TXA_2)的含量。结果透热电凝组的含量比对照组显著升高。证明PGE_2、PGI_2和TXA_2参与了透热电凝对眼的伤性反应作用,是引起术后炎症反应的重要因素。提示在视网膜脱离术前及术后,眼局部应用非甾体类抗炎药物(NSAID)可有效地减轻术后炎症反应及预防黄斑囊样水肿的发生。
The surface of the non-ocular sclera was electrocoagulatively assayed for the content of protein (PRO), prostaglandin E_2 (PGE_2), prostacyclin (PGI_2) and thromboxane (TXA_2) in aqueous humor. Results The content of the thermocoagulation group was significantly higher than that of the control group. It is proved that PGE_2, PGI_2 and TXA_2 are involved in the traumatic reaction of diathermy to the eye, which is an important factor in the postoperative inflammatory response. It is suggested that non-steroidal anti-inflammatory drugs (NSAIDs) may be effective in reducing postoperative inflammatory reaction and preventing cystoid macular edema before and after retinal detachment.