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１引言 白血病治疗失败的主要原因是白血病细胞产生多药耐药（ＭＤＲ），是白血病治疗有待解决的问题。我们采用化学药物联合耐药修饰剂治疗１０例Ｐ－糖蛋白阳性和多药耐药基因（ＭＤＲ１）高表达的难治性急性非淋巴细胞白血病（ＡＮＬＬ），取得一定疗效，现报告如下。２资料
1 Introduction The main reason for the failure of leukemia treatment is that leukemia cells produce multidrug resistance (MDR), which is a problem to be solved in the treatment of leukemia. We use chemical drug resistance modifier treatment of 10 cases of P-glycoprotein-positive and multi-drug resistance gene (MDR1) expression of refractory acute non-lymphocytic leukemia (ANLL), and achieved a certain effect, are as follows. 2 information