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目的探讨消化性溃疡合并上消化道出血患者采用潘妥拉唑钠注射液治疗的疗效。方法选择我院2012年11月~2014年11月收治的消化性溃疡合并上消化道出血患者200例作为研究对象,随机将其分为潘妥拉唑组160例和奥美拉唑组40例。奥美拉唑组患者静脉滴注100 mL含量为0.9%氧化钠+奥美拉唑注射液40 mg,潘妥拉唑组静脉滴注100 mL含量为0.9%氧化钠+潘妥拉唑注射液40 mg,结果潘妥拉唑组总有效率100%,其中无效0例,有效8例(5%),显效152例(95%);奥美拉唑组总有效率85%,其中无效6例(15%),有效8例(20%),显效26例(65%),两组患者的总有效率比较,差异有统计学意义(P<0.05)。结论消化性溃疡合并上消化道出血患者采用潘妥拉唑钠注射液治疗的疗效较佳,安全可靠,没有不良反应及毒副作用,值得推广应用。
Objective To investigate the curative effect of pantoprazole sodium injection in patients with peptic ulcer complicated with upper gastrointestinal bleeding. Methods 200 cases of patients with peptic ulcer complicated with upper gastrointestinal hemorrhage admitted in our hospital from November 2012 to November 2014 were selected as the research object and randomly divided into 160 cases in the group of ptolazole and 40 cases in the omeprazole group . Omeprazole group patients intravenously drip 100 mL 0.9% sodium oxide + omeprazole injection 40 mg, intravenous infusion of 100 mL of the content of the pandurazole group 0.9% sodium oxide + pantoprazole injection 40 mg. The total effective rate was 100% in the group of pantoprazole, of which 0 was ineffective, 8 (5%) effective and 152 markedly effective (95%). The total effective rate was 85% in omeprazole group, of which 6 Cases (15%), effective in 8 cases (20%), markedly effective in 26 cases (65%), the total effective rate of two groups of patients, the difference was statistically significant (P <0.05). Conclusion Peptic ulcer patients with upper gastrointestinal bleeding treated with pantoprazole sodium better efficacy, safe, reliable, no adverse reactions and side effects, it is worth promoting the application.