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The coincidence of relevant factors, e.g. oxygen absorption quantity, weight increment, water soluble iron ions and sulfate ion of sulfide ore samples in the oxidation process, was tested through experiment. Based on a large number of tests for a group sample of sulfide ores from a mine, some important conclusions were obtained. The results obtained by the investigation indicate that there is no general interpretation relative to the oxygen absorption and the formation products of sulfate ion and water soluble iron ions during the oxidation process of sulfide ores at ambient temperature. However, the weight increment of the sulfide ore samples in the oxidation process at ambient temperature has a linear relationship with the quantity of oxygen absorption.