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目的：观察西沙必利对功能性消化不良（ＦＤ）胆囊排空延缓病人的促胆囊排空作用。方法：按双盲随机将病人５２例分为２组，西沙必利组（男性１４例，女性１２例，年龄３６±ｓ９ａ）用西沙必利５ｍｇｐｏ，ｔｉｄ×４ｗｋ；安慰剂组（男性１１例，女性１５例，年龄３７±８ａ）用安慰剂１片ｐｏ，ｔｉｄ×４ｗｋ，于脂餐前后以Ｂ超分别测定胆囊最大长径、横径及前后径。结果：剩余容量、胆囊最大排空率及胆囊收缩至最小的时间西沙必利组与安慰剂组相比差别有显著意义（Ｐ＜０．０５），治疗组症状较对照组明显改善。结论：西沙必利治疗功能性消化不良对胆囊排空延缓有效。
Objective: To observe the effect of cisapride on promoting gallbladder emptying in patients with functional dyspepsia (FD) and gallbladder emptying. Methods: Fifty-two patients were randomized into two groups according to a double-blind randomized trial. Patients in the cisapride group (14 males and 12 females, age 36 ± s9a) were treated with cisapride 5mgpo, tid × 4wk and placebo (11 males , 15 females, age 37 ± 8a) with placebo 1 po, tid × 4wk, measured before and after the meal with B ultrasound were the largest diameter, diameter and anteroposterior diameter of the gallbladder. Results: There was significant difference between the cisapride group and the placebo group (P <0.05), the residual volume, the maximal emptying rate of the gallbladder and the time to the gallbladder contraction. The symptoms in the treatment group were significantly improved compared with the control group. Conclusion: Cisapride treatment of functional dyspepsia is effective in retarding the emptying of gallbladder.