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目的：探讨慢性乙型肝炎患者血清ＴＮＦα、ｓＩＬ－２Ｒ与中医证型的关系。方法：１６２例慢性乙型肝炎患者按中医辨证分成５型，同时以ＥＬＩＳＡ检测血清中肿瘤坏死因子α、可溶性白细胞介素２受体的水平。结果：湿热内阻型和瘀血阻络型血清肿瘤坏死因子α和可溶性白细胞介素２受体水平明显高于其他证型，肝郁脾虚型和脾肾阳虚型最低。结论：血清肿瘤坏死因子α和可溶性白细胞介素２受体水平与中医证型密切相关。
Objective: To investigate the relationship between serum TNFα, sIL-2R and TCM syndromes in patients with chronic hepatitis B Methods: 162 chronic hepatitis B patients were divided into 5 types according to syndrome differentiation of traditional Chinese medicine. At the same time, the levels of tumor necrosis factor - α and soluble interleukin - 2 receptor were detected by ELISA. Results: The levels of Tumor Necrosis Factor-α and Soluble Interleukin-2 Receptor in the heat-damp internal resistance type and blood-stasis-obstructing blood serum were significantly higher than those in other syndromes. The liver-spleen qi deficiency type and spleen-kidney yang deficiency type were the lowest. Conclusion: The levels of tumor necrosis factor - α and soluble interleukin - 2 receptor are closely related to TCM syndromes.