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目的评价妈咪爱对新生儿生理性黄疸消退治疗的疗效和安全性。方法检索CBMdisc、CNKI库、万方数据库,对文献质量进行评价,由Revman 5.0软件分析研究数据。观察指标为治疗后的血清胆红素日均下降值、血清胆红素值、黄疸消退时间及不良反应。结果经筛选后有22项对照研究纳入,文献质量评价为C级。将文献分为2类研究:试验组采用妈咪爱治疗,对照组为空白对照;常规对照组为常规治疗,试验组在常规治疗基础上加用妈咪爱治疗。试验组与空白对照组相比血清胆红素值MD=-59.59[-70.49,-48.69],试验组与常规对照组相比胆红素日均下降值MD=15.07[10.07,20.07],血清胆红素值MD=-36.22[-55.42,-17.03],黄疸消退时间MD=-1.39[-1.73,-1.04];基本无严重不良反应报道。结论研究文献合并分析表明妈咪爱有助于治疗新生儿生理性黄疸,且安全性高。
Objective To evaluate the efficacy and safety of Mommy Love in the treatment of neonatal jaundice. Methods CBMdisc, CNKI library and Wanfang database were searched and the quality of the literature was evaluated. Revman 5.0 software was used to analyze the data. Observed indicators for the treatment of serum bilirubin daily average decline in serum bilirubin values, jaundice subsided time and adverse reactions. Results After screening, 22 control studies were included, and the quality of the literature was rated as Grade C. The literature is divided into two types of studies: the experimental group adopted Mommy love treatment, the control group as a blank control; conventional control group for conventional treatment, the experimental group in the conventional treatment plus Mommy love treatment. Compared with the blank control group, the serum bilirubin value in the experimental group was -59.59 [-70.49, -48.69], the average daily decline value of bilirubin in the experimental group was 15.07 [10.07,20.07] compared with the conventional control group, the serum Bilirubin value MD = -36.22 [-55.42, -17.03], jaundice regression time MD = -1.39 [-1.73, -1.04]; no serious adverse reactions were reported. Conclusions The merger and analysis of the research literature shows that Mommy love helps to cure neonatal jaundice and is safe.