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目的探讨手足口病发病危险因素。方法采用病例对照研究方法,以2015年在保定市儿童医院住院的手足口病患儿为病例组,以同居住地、患儿发病前2周内无手足口皮疹和发热病史的儿童为对照组,进行单因素和多因素非条件Logistic回归分析。结果单因素分析显示:发病前10 d内去过医疗机构、照看人学历较低、家中有其他14岁以下儿童、儿童没有独立的餐具和毛巾等是危险因素,照看人知道如何预防手足口病、餐具定期煮烫、玩具定期清洗是保护因素。多因素分析显示:餐具不定期进行煮烫消毒、没有对儿童的玩具进行定期清洗消毒、发病前10 d内去过医疗机构、家中有其他10岁以下儿童是发病危险因素。结论医院内感染、隐性感染和轻型病例的家庭引入是手足口病的主要危险因素。手足口病预防应该主要从加强医院内感染控制,全方位的消毒措施保护等方面入手。
Objective To explore the risk factors of hand-foot-mouth disease. Methods A case-control study was conducted. Children with hand-foot-mouth disease who were hospitalized in Children’s Hospital of Baoding in 2015 were selected as the case group. Children with no history of hand-foot-mouth rash and fever in the same place of residence and children within 2 weeks before onset were used as control group. Univariate and multivariate non-conditional logistic regression analysis. Results Univariate analysis showed that medical institutions were visited within 10 days prior to the onset of illness. Caregivers had a low education level. Other children under 14 years of age did not have children with independent tableware and towels as risk factors. Caregivers knew how to prevent HFMD , Tableware regularly cook hot, regular cleaning toys is a protective factor. Multivariate analysis showed that tableware was blanched irregularly, children’s toys were not regularly cleaned and disinfected, and medical institutions were visited within 10 days prior to the onset of disease. Other children under 10 years old were risk factors for morbidity. Conclusion The introduction of family nosocomial infections, latent infections and light cases are the major risk factors for HFMD. Hand, foot and mouth disease prevention should be mainly from strengthening the hospital infection control, a full range of disinfection measures to protect and so on.