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目的探讨卡维地洛对合并充血性心力衰竭的劳力型心绞痛患者治疗效果。方法对35例合并充血性心力衰竭的劳力型心绞痛患者应用卡维地洛,观察治疗前后血压、静息状态下心率、心肌耗氧量、心电图、LVEF值的变化,从而评定卡维地洛治疗效果。结果通过观察卡维地洛治疗6w前后血压、静息状态下心率、心肌耗氧量、心电图、LVEF值的变化,治疗前后比较有显著性差异,P<0.01。结论卡维地洛对合并充血性心力衰竭的劳力型心绞痛,特别是对于NYHA分级Ⅲ以上,LVEF30以下的病例疗效肯定,在无禁忌症的情况下,从小剂量开始尽早应用是安全有效的。
Objective To investigate the therapeutic effect of carvedilol on patients with labor-type angina pectoris complicated with congestive heart failure. Methods Carvedilol was applied to 35 patients with labor-type angina pectoris with congestive heart failure. The changes of blood pressure, resting heart rate, myocardial oxygen consumption, electrocardiogram and LVEF were observed before and after treatment to evaluate the effect of carvedilol effect. Results By observing the changes of blood pressure, resting heart rate, myocardial oxygen consumption, electrocardiogram and LVEF before and after carvedilol treatment, there were significant differences before and after treatment (P <0.01). CONCLUSION Carvedilol is effective in patients with angina pectoris with congestive heart failure, especially those with NYHA class III or higher and LVEF30 or lower. In the absence of contraindications, it is safe and effective to use it as early as possible from a small dose.