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报告108例17～51岁HBsAg阳性携带者1984～1986年用RPHA(反向间接血凝法)检测HBsAg,改良赖氏法测定SGPT,常规方法测定黄疸指数、TTT、TFT及临床体格检查的随访结果。1.据107例统计,HBsAg三年内阴转22例,阴转率20.56％,其中5例为有病史者;30及30岁以上组阴转率30％(12/40)高于30岁以下之14.93％(10/67),但两者间之差异仍不显著,x~3=3.49,P>0.05;滴度显著降低者56侧。2.全组108例三年内发展成原发性肝癌并死亡者一例;余107例中先后记录为各型急、慢性(乙型)肝炎者共24例(22.43％);1984年记录的16例临床肝炎患者三年内一例阴转,4例肝功能恢复、症征消失,成为肝炎后HBsAg携带者,11例仍有症征。全组108例内有肝炎家族史的26例中,一例即上述的原发性肝癌,余25例无一转阴,7例(28％)先后记录为慢性(乙型)肝炎。
108 cases of HBsAg positive carriers aged 17-51 years were enrolled in this study. HBsAg was detected by RPHA (reverse indirect hemagglutination) from 1984 to 1986, and SGPT was determined by modified Lai’s method. The follow-up of jaundice index, TTT, TFT and clinical physical examination result. 1. According to 107 statistics, HBsAg within three years, 22 cases of vaginal conversion, negative conversion rate of 20.56%, of which 5 were with a history; 30 and 30 years of age group overcast rate of 30% (12/40) higher than 30 years of age (14.93%, 10/67), but the difference between the two groups was still not significant, x ~ 3 = 3.49, P> 0.05; 2. A total of 108 cases of primary hepatocellular carcinoma (HCC) were found and died in three years. Among the 107 cases, 24 cases (22.43%) were recorded as acute and chronic hepatitis B (22.43%) in 1984 and 16 Cases of patients with hepatitis in three cases overcast within one year, 4 cases of liver function recovery, symptoms disappear, become hepatitis B after HBsAg carriers, 11 cases are still signs. Of the 108 patients who had a family history of hepatitis in one hundred and twenty-eight patients, one of them had the above-mentioned primary liver cancer, the other 25 patients had no metastasis, and seven patients (28%) were recorded as chronic hepatitis B in succession.