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龋病是人类最常见的感染性疾病之一,严重威胁人群口腔健康。变形链球菌组细菌,主要是Streptococcus mutans和Streptococcus sobrinus被认为是最重要的致龋微生物。动物实验和临床研究已证实,通过免疫学干预致龋菌在口腔的定植能够影响龋病的发生,防龋疫苗有望成为一种新的龋病预防措施。
Caries is one of the most common human infectious diseases, a serious threat to oral health of the population. Streptococcus mutans and Streptococcus sobrinus are considered to be the most important cariogenic microorganisms in the group of Streptococcus mutans. Animal experiments and clinical studies have confirmed that oral caries can be affected by cariogenic bacteria caused by immunological intervention. Caries-preventive vaccines are expected to become a new caries preventive measure.