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目的:通过分析中药引起过敏性休克的相关因素,为合理用药提供参考。方法:收集1997～2007年《药物不良反应杂志》报道的有关过敏性休克的病例资料,进行整理、汇总、分析。结果:可导致过敏性休克的中药中,穿琥宁注射液居首位,占21.43%,葛根素注射液次之,占12.50%;给药途径以静脉用药发生率最高,占92.85%;发生时间以速发型过敏性休克多见;过敏性休克的发生与性别、年龄无关。结论:临床用药前应详细询问过敏史,严格用药指征,选择合适的给药途径,备齐抢救设备,仔细观察用药后反应,以确保用药安全。
Objective: To analyze the related factors of anaphylactic shock caused by traditional Chinese medicine and to provide a reference for rational drug use. Methods: The data of cases related to anaphylactic shock reported in Journal of Adverse Drug Reactions from 1997 to 2007 were collected, collated, summarized and analyzed. Results: Chuanhuning injection accounted for 21.43% of the traditional Chinese medicines that can cause anaphylactic shock, puerarin injection took the second place, accounting for 12.50%; the highest incidence of intravenous administration was 92.85% Frequent haemorrhagic anaphylactic shock more common; the occurrence of anaphylactic shock and gender, age has nothing to do. Conclusion: Before clinical medication should be asked in detail allergy history, strict indications for medication, choose the appropriate route of administration, ready rescue equipment, careful observation of the response after medication to ensure drug safety.