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目的 探讨急性脑梗死的动脉内超早期溶栓治疗。方法 对 1996年 8月～ 2 0 0 0年 2月用尿激酶进行超早期 (发病至溶栓时间 <6h)动脉内接触性溶栓治疗 17例急性脑梗死病例进行回顾性分析。结果 17例病人血栓或栓子位置分别为 :大脑中动脉M1段 10例 ,大脑前动脉A段 1例 ,大脑后动脉P段 1例 ,椎 基底动脉 5例。溶栓后血管再通 15例 ,但 11例有残余狭窄。临床症状完全恢复者12例 ,部分恢复者 3例 ,死亡 2例。结论 超早期的动脉内尿激酶接触性溶栓是急性脑梗死治疗的比较安全有效的方法之一
Objective To investigate the ultra-arterial thrombolysis in patients with acute cerebral infarction. Methods A retrospective analysis of 17 cases of acute cerebral infarction treated by intra-arterial thrombolytic therapy with urokinase in early stage (onset to thrombolysis time <6 h) from August 1996 to February 2000 was performed. Results Thromboembolism and embolism were found in 17 patients with 10 cases of middle cerebral artery M1, 1 case of anterior cerebral artery A, 1 case of posterior cerebral artery P, and 5 cases of vertebrobasilar artery. Thrombolysis after revascularization in 15 cases, but 11 cases of residual stenosis. 12 cases of complete recovery of clinical symptoms, 3 cases of partial recovery and 2 cases of death. Conclusion Ultra-early intra-arterial Urokinase contact thrombolysis is one of the safe and effective methods for the treatment of acute cerebral infarction