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目的：研究紫外线照射充氧自血回输疗法（ＵＢＩＯ）对脑梗塞患者血浆内皮素（ＥＴ）和一氧化氮（ＮＯ）含量的影响。方法：应用ＵＢＩＯ治疗脑梗塞患者４８例，检测患者治疗前及治疗１疗程后血浆ＥＴ和ＮＯ变化，并与同龄健康查体者２５名进行对照。结果：脑梗塞患者ＵＢＩＯ治疗１疗程后显著降低血浆ＥＴ水平，治疗前后分别为（６０．０３±１９．４０）ｎｇ／ｍｌ，（３８．２９±１７．５０）ｎｇ／ｍｌ，提高ＮＯ含量，治疗前后分别为（３５．９３±９．８０）μｍｏｌ／Ｌ，（５０．０４±１０．９０）μｍｏｌ／Ｌ，并可降低ＥＴ／ＮＯ比值。结论：应用ＵＢＩＯ治疗能有效地改变脑梗塞患者血浆ＥＴ与ＮＯ含量。
Objective: To investigate the effect of UBIO on the levels of plasma endothelin (ET) and nitric oxide (NO) in patients with cerebral infarction. Methods: Forty-eight patients with cerebral infarction were treated with UBIO. The changes of ET and NO in plasma before treatment and after one course of treatment were detected and compared with 25 healthy controls of the same age. Results: The levels of ET in plasma of patients with cerebral infarction after UBIO treatment for one week were significantly lower than those before treatment (60.03 ± 19.40 ng / ml, (38.29 ± 17.50) ng / ml, respectively) Before and after treatment were (35.93 ± 9.80) μmol / L and (50.04 ± 10.90) μmol / L respectively, and the ET / NO ratio could be decreased. Conclusion: UBIO treatment can effectively change the content of plasma ET and NO in patients with cerebral infarction.